NCT06605846Completed
Otago Exercises on the Risk of Falling in Prostatic Cancer Patients Receiving Androgen Deprivation Therapy
Source: ClinicalTrials.gov · Last updated 2 Apr 2025
Brief summary (registry, in English)
Androgen deprivation therapy (ADT) is a common treatment for older men with advanced prostate cancer (PCa) but is associated with numerous deleterious health effects that may accentuate age associated physiological declines. Decreased lower body muscle mass and strength, cognitive decline, worsen fatigue and progressive loss of BMD following initiating ADT could put prostate cancer survivors at higher risk of impaired physical functioning performance and subsequently developing falls. Otago training is helpful, and one of the most powerful interventions where the original randomized controlled trials reported improvements in functional outcomes and a 35% reduction in falls for frail, high-risk older adults (Shubert et al., 2018). In Egypt, there are little researches about Otago Exercise Program.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 110 (actual)
- First submitted
- 18 Sept 2024
- Start date
- 23 Sept 2024
- Primary completion date
- 1 Apr 2025
- Lead sponsor
- MTI University
- Diseases
- Prostate cancer
- NCT number
- NCT06605846
What you commit to
- Study type: Interventional
- Participants enrolled: 110
- From 23 Sept 2024 to the primary completion date, 1 Apr 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- severe cardiac disease (New York Heart Association class III or greater), angina,
- uncontrolled hypertension (blood pressure \> 160/95 mmHg), moderate to severe aortic stenosis, acute illness or fever, uncontrolled atrial or ventricular dysrhythmias, uncontrolled sinus tachycardia (\> 120 beats per minute), third-degree atrioventricular heart block
Other
- lower limb fracture within last 3 months , lower limb amputation
Who the study is looking for
- Men aged 50 years or older diagnosed with adenocarcinoma prostate cancer.
- Will initiate and receive continuous ADT (luteinizing hormone releasing hormone agonist (LHRH) or combination of LHRH and anti-androgen) for at least 6 months after recruitment.
- Report \> 1 fall in the past year OR have a score on one of two physical performance tests that is associated with increased fall risk (i.e., ≥ 12.0 s to complete the 3 m timed up and go (TUG)
- Willing to attend \>75% of intervention Otago exercises
Age in the registry: 50 years to 75 years · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| MTI university Coordinator of this site? Confirm its status | Multiple Locations | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.