NCT06606028Recruiting
Tumor-Informed ctDNA Testing for MRD Following Treatment of Squamous Cell Carcinoma
Tumor-informed ctDNA Testing for Minimal Residual Disease Monitoring Following Curative-intent Treatment of Squamous Cell Carcinoma of the Head and Neck.
Source: ClinicalTrials.gov · Last updated 12 Dec 2025
Brief summary (registry, in English)
This is a single-center, non-interventional, observational study that evaluates the correlation of circulating tumor DNA (ctDNA) testing to cancer relapse for participants with squamous cell carcinomas (HNC) of the head and neck mucosa and skin after curative-intent primary radiation or surgery.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 250 (estimated)
- First submitted
- 18 Sept 2024
- Start date
- 9 Oct 2024
- Primary completion date
- 30 Dec 2028
- Lead sponsor
- University of California, San Francisco
- Diseases
- Head and neck cancer
- NCT number
- NCT06606028
What you commit to
- Study type: Observational
- Planned participants: 250
- From 9 Oct 2024 to the primary completion date, 30 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- 1\. Contraindication to phlebotomy for removal of 20 mL of peripheral blood each time point (up to 300 mL total over 15 time points).
Who the study is looking for
- Participants must have histologically or cytologically confirmed squamous cell carcinoma of the head and neck mucosa and skin.
- Participants must be age \>=18 years.
- Participants must be planning to receive curative-intent surgery or radiation-based treatment as part of standard of care treatment.
- Participants must have the ability to understand and the willingness to sign a written informed consent document.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.