NCT06606288Active, not recruiting
Characterizing Outcomes and Real-World Experience of Cardiac Physiologic Pacing (The CORE-CPP Study)
Source: ClinicalTrials.gov · Last updated 29 Apr 2026
Brief summary (registry, in English)
The purpose of this study is to use real-world evidence to validate that conduction system pacing (CSP), delivered via a Medtronic 3830 catheter-delivered lead and a Medtronic dual-chamber transvenous pacemaker, is a safe and effective alternative to biventricular pacing (BVP) in patients indicated for cardiac resynchronization therapy (CRT) to deliver cardiac physiologic pacing (CPP), as documented in the clinical literature.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 6000 (estimated)
- First submitted
- 18 Sept 2024
- Start date
- 1 Jan 2017
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Medtronic Cardiac Rhythm and Heart Failure
- Diseases
- Heart failure
- NCT number
- NCT06606288
What you commit to
- Study type: Observational
- Planned participants: 6000
- From 1 Jan 2017 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Evidence of a prior CIED device.
- Less than 12 months continuous enrollment in Medicare Part A and Part B prior to implant date.
- Evidence of a prior CIED device.
- Less than 12 months continuous enrollment in Medicare Part A and Part B prior to implant date.
Other
- Dual-chamber CSP cohort:
- Non-Medtronic pacemaker (unable to link to Medtronic device registration data).
- Missing lead type or placement data.
- Lead type and placement data indicating non-CSP placement.
- BVP comparator cohort:
- Non-Medtronic pacemaker (unable to link to Medtronic device registration data).
- Missing lead type or placement data.
Who the study is looking for
- Dual-chamber CSP cohort:
- Medicare beneficiaries implanted with a Medtronic dual-chamber transvenous pacemaker on or after the study start date.
- Lead type and placement data indicating CSP.
- An indication for CRT.
- BVP comparator cohort:
- Medicare beneficiaries implanted with a Medtronic biventricular pacemaker (CRT-P) on or after the study start date.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medtronic Coordinator of this site? Confirm its status | Mounds View | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.