NCT06607913Recruiting
Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength
BCCMA: Recovery of Aged Muscle After Disuse Atrophy (REMEDY): Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength (EMPHASIS)
Source: ClinicalTrials.gov · Last updated 7 Apr 2026
Brief summary (registry, in English)
The aging Veteran population has more frequent inpatient hospitalization than non-Veterans. In addition, older Veterans have an inability to fully recover muscle mass and function after hospital-acquired weakness. The problem of hospital-acquired weakness is greatly increased in at-risk Veteran populations such as those with chronic kidney disease (CKD). The purpose of this collaborative study involving Denver and Baltimore VAMC sites is to improve health through the detection and rehabilitation management of hospital-acquired weakness in those with CKD. The study goals include identifying and monitoring the optimal muscle assessment sites in clinical settings, examining how muscle health impacts length of hospital stay and physical resilience, and determining how home-based and supervised exercise comparatively addresses post-hospitalization physical resilience using performance tests and Veteran feedback.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 250 (estimated)
- First submitted
- 19 Sept 2024
- Start date
- 11 Apr 2025
- Primary completion date
- 30 Sept 2028
- Lead sponsor
- VA Office of Research and Development
- Diseases
- Chronic kidney disease
- NCT number
- NCT06607913
What you commit to
- Study type: Interventional
- Planned participants: 250
- From 11 Apr 2025 to the primary completion date, 30 Sept 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cardiovascular risk: Poorly controlled hypertension (\>160/100)
- Coronary event in past 6 months
- Class III or IV CHF
- symptomatic angina at rest or during exercise
- Syncope in past year, without known resolution of cause
- Contraindications to resistance training, including history of intracranial or retinal bleeding; Diabetes with active proliferative retinopathy
- History of significant spinal osteoarthritis or spinal stenosis
- Dementia (on medical record review or mini-mental status exam score)
Other
- COPD requiring home oxygen
Who the study is looking for
- Age \> 55 years
- Diagnosis of stage 3-4 CKD or an eGFR of \<45 mL/min/1.73m2
Age in the registry: 55 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rocky Mountain Regional VA Medical Center, Aurora, CO Coordinator of this site? Confirm its status | Aurora | United States | Recruiting |
| Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD Coordinator of this site? Confirm its status | Baltimore | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.