NCT06608121Completed
Upper Limb Muscle Strength Models for Patients With Motor Impairment.
Study for the Development and Evaluation of Personalised Muscle Effort Generation Models for Patients With Upper Limb Motor Deficits
Source: ClinicalTrials.gov · Last updated 3 Dec 2025
Brief summary (registry, in English)
Upper limb motor impairments are common. They affect quality of life and can lead to dependency. They are mainly due to neurological conditions such as stroke, multiple sclerosis, and traumatic spinal cord injury. However, the contractile properties of muscle, in particular the maximum force that can be generated voluntarily (MVF) depending on joint angle and motion speed, have been mainly studied and modeled in healthy people. This study aims at developing mathematical models describing residual muscle forces in patients with motor impairments. The knowledge could guide patients' rehabilitation and could be useful for the development of robotic assistance systems that use patients\' residual capacities to control the level of assistance provided.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 32 (actual)
- First submitted
- 19 Sept 2024
- Start date
- 5 Nov 2024
- Primary completion date
- 22 Oct 2025
- Lead sponsor
- Pôle Saint Hélier
- Diseases
- Stroke, Multiple sclerosis
- NCT number
- NCT06608121
What you commit to
- Study type: Interventional
- Participants enrolled: 32
- From 5 Nov 2024 to the primary completion date, 22 Oct 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cognitive impairment that may interfere with measurements (MOCA \< 20/30)
- Decompensated heart disease or other unbalanced pathology which contraindicates or may hinder isokinetic testing.
Other
- Spasticity \>3/4 on the Aschworth scale in the shoulder abductor or elbow flexor muscles.
- Presence of a pressure sore \> stage 2 at the ischial level
- Recent trauma to limbs or spine
- Persons deprived of their liberty by a judicial or administrative decision
- Pregnant women, women in labour or nursing mothers.
Who the study is looking for
- Patients aged between 18 and 85
- A patient who is a member or beneficiary of a social security scheme
- Patients hospitalised at the Saint-Hélier rehabilitation centre for a stroke more than 15 days old, MS or SCI
- Patients with a motor deficit ≤3/5 on the MRC (Medical Research Council) scale in both internal-external shoulder rotation and elbow flexion-extension.
- Patient with voluntary consent to participate in this study.
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fondation Saint-Hélier Coordinator of this site? Confirm its status | Rennes | France | Unknown status |
Related publications
- Are Isokinetic Torque-Angle Models Derived from Healthy Subjects Applicable to Patients with Upper-Limb Neurological Motor Impairment?Ann Biomed Eng · 2026 · PMID 41724899
This page is information, not medical advice. Discuss any trial with your doctor.