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NCT06608147Recruiting

MOLyF : Bone Marrow and Follicular Lymphoma

Bone Marrow and Follicular Lymphoma

Source: ClinicalTrials.gov · Last updated 10 Dec 2024 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

This is a prospective single-center study designed to assess potential differences in cell composition between bone marrows of patients with follicular lymphoma and those from control subjects. Follicular lymphoma is the most common indolent lymphoma. It is characterised by systematic relapses and bone marrow dissemination in 70% of patients at the time of diagnosis. Although relapses are thought to be related to refractory tumour cells nested in a supportive microenvironment in the bone marrow, the mechanisms involved are poorly understood. To study the specificities of the bone marrow of patients with follicular lymphoma, It is necessary to compare them with control samples. This study takes advantage of surgeries involving sternotomies to recover lost bone marrow and establish a bone marrow bank of patients without hematological disease. This bank will be used to set up control cohorts for other clinical trials involving patients with follicular lymphoma.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
200 (estimated)
First submitted
19 Sept 2024
Start date
4 Dec 2024
Primary completion date
1 Oct 2034
Lead sponsor
Rennes University Hospital
NCT number
NCT06608147

What you commit to

  • Study type: Interventional
  • Planned participants: 200
  • From 4 Dec 2024 to the primary completion date, 1 Oct 2034
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of haematological malignancy or haemogram disturbance

Other

  • Immunomodulating treatment: immunosuppressants, corticoids, antineoplastics
  • Persons covered by articles L. 1121-5 to L. 1121-8 and L. 1122-1-2 of the French Public Health Code (e.g. minors, protected adults, etc.)\].

Who the study is looking for

  • Major patient
  • Patient hospitalized in the thoracic, cardiac and vascular surgery department for surgery involving a sternotomy
  • Patient with free, informed, written consent
  • Patient covered by a health insurance scheme

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
CHU Rennes
Coordinator of this site? Confirm its status
RennesFranceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.