NCT06612437Completed
Optimization of Time Parameters of Priming iTBS for Poststroke Motor Rehabilitation
Source: ClinicalTrials.gov · Last updated 6 Jan 2026
Brief summary (registry, in English)
The goal of this clinical trial is to identify the effect of different time intervals between continuous theta burst stimulation (cTBS) and intermittent theta burst stimulation(iTBS), on top of a standard robot-assisted training (RAT) for sensorimotor rehabilitation in patients with chronic stroke. Using electroencephalography (EEG) to explore potential sensorimotor neuroplasticity underying stroke.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 62 (actual)
- First submitted
- 21 Sept 2024
- Start date
- 1 Oct 2024
- Primary completion date
- 1 Dec 2025
- Lead sponsor
- The Hong Kong Polytechnic University
- Diseases
- Stroke
- NCT number
- NCT06612437
What you commit to
- Study type: Interventional
- Participants enrolled: 62
- From 1 Oct 2024 to the primary completion date, 1 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- diagnosis of any clinically significant or unstable medical disorder.
- a history of neurological or psychiatric disease excluding stroke, or current use of psychoactive medication (sedatives, antipsychotics, antidepressants, etc.).
Other
- any contraindications to TMS based on the TMS safety guidelines (Rossi, Hallett, Rossini, \& Pascual-Leone, 2011).
- inability to follow treatment instructions due to severe cognitive (using the Hong Kong version of the Montreal Cognitive Assessment (MoCA-HK) \< 22/30) and communication deficiency.
- extreme spasticity over the hemiparetic upper limb (Modified Ashworth Score\>2) or severe pain that hindered movement.
Who the study is looking for
- diagnosis of hemorrhagic or ischemic stroke using computed tomography (CT) or magnetic resonance imaging (MRI).
- the first-ever stroke with unilateral hemiplegia.
- 18-75 years old.
- chronic stroke ( ≥ 6 months).
- residual hemiparetic upper limb functional level in the Functional Test for the Hemiplegic Upper Extremity (FTHUE-HK) ≥ 2.
- can understand and read Chinese.
- signed informed consent.
Age in the registry: 18 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Hong Kong Polytechnic University Coordinator of this site? Confirm its status | Hong Kong | Hong Kong SAR China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.