NCT06614400Completed
The RETRAIN Trial (Phase 1)
MonitoRing the Effect of TRAnscutaneous Functional electrIcal Stimulation of the Common Peroneal Nerve on Cerebral Haemodynamics in Patients With Ischaemic Strokes. A Single Centre Prospective Study (Phase 1).
Source: ClinicalTrials.gov · Last updated 25 Mar 2025
Brief summary (registry, in English)
The primary objective is to investigate in stroke patients the impact of geko™ NMES treatment, when used as standard of care for VTE prevention, on brain haemodynamics at different stimulation levels and in three different postural positions (supine, semi-supine \[45° seated\] and seated). The aim is to identify the optimal stimulation level and postural position for the maximum response (NMES versus no NMES) with regard to relative total haemoglobin concentration (i.e., the sum of relative deoxyhaemoglobin and oxyhaemoglobin concentrations) using fNIRS and EEG.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 18 (actual)
- First submitted
- 28 Aug 2024
- Start date
- 8 Oct 2024
- Primary completion date
- 8 Mar 2025
- Lead sponsor
- Countess of Chester NHS Foundation Trust
- Diseases
- Stroke
- NCT number
- NCT06614400
What you commit to
- Study type: Observational
- Participants enrolled: 18
- From 8 Oct 2024 to the primary completion date, 8 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Stroke survivors with ischaemic stroke less than 7 days from onset.
- History of epilepsy.
- History of established peripheral neuropathy.
Other
- Inability to gain consent from the patient.
- A transient ischaemic attack (TIA).
- Below/above knee amputation.
- Too unwell to participate as judged by physician.
- Use of any other neuromodulation device that may interact with NMES
Who the study is looking for
- Adult over 18
- Patient with ischaemic stroke diagnosis confirmed by a stroke physician.
- No intracerebral haemorrhage as ruled out by computerised tomography (CT) or MRI scan.
- Able to achieve a supine, sitting and semi-sitting position of 45° with the help of another person.
- Receiving geko™ NMES treatment as standard of care for VTE prevention
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Countess of Chester Hospital NHS Foundation Trust Coordinator of this site? Confirm its status | Chester | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.