NCT06616831Completed
At-Home taVNS - Stroke Rehab
Development of At-Home Transcutaneous Auricular Vagus Nerve Stimulation for Post-Stroke Rehabilitation
Source: ClinicalTrials.gov · Last updated 13 Aug 2026
Brief summary (registry, in English)
Early evidence suggests the benefits of post-stroke motor rehabilitation may be enhanced by applying electrical stimulation to the ear. This study aims to test the new approach of pairing ear stimulation with motor rehabilitation in the home setting in stroke survivors with upper limb motor function deficits.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 5 (actual)
- First submitted
- 12 Aug 2024
- Start date
- 28 Oct 2024
- Primary completion date
- 26 Mar 2025
- Lead sponsor
- Medical University of South Carolina
- Diseases
- Stroke
- NCT number
- NCT06616831
What you commit to
- Study type: Interventional
- Participants enrolled: 5
- From 28 Oct 2024 to the primary completion date, 26 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Other concomitant neurological disorders affecting upper extremity motor function;
- Prior injury to vagus nerve;
- Botox injections within 4 weeks of the first day of rehabilitation therapy.
Other illness
- Documented history of dementia before or after stroke;
- Documented history of uncontrolled depression or psychiatric disorder either before or after stroke which could affect their ability to participate in the experiment;
- Uncontrolled hypertension;
Other
- Presence of Dysphagia or aspiration difficulties;
- Pregnancy;
Who the study is looking for
- 18-80 years old with an ischemic or hemorrhagic stroke that occurred ≥6 months prior;
- Ability to give consent;
- Unilateral limb (left or right) weakness with Fugl Meyer-Upper Extremity Scale score of 19-53/60 points which indicates adequate arm/hand use for rehabilitation tasks;
- active wrist flexion/extension ≥10° with active abduction/extension of thumb and at least 1 digit ≥10° to further assure ability to participate in rehabilitation tasks;
- Passive range of motion in affected shoulder, elbow and wrist within 20 degrees of normal values.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of South Carolina Coordinator of this site? Confirm its status | Charleston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.