NCT06618495CompletedPhase 1/2
Clinical Study and Molecular Mechanism of Xuesaitong Soft Capsule in the Treatment of Acute Coronary Syndrome
Clinical Study and Molecular Mechanism of Xuesaitong Soft Capsule in the Treatment of Acute Coronary Syndrome After Percutaneous Coronary Intervention
Source: ClinicalTrials.gov · Last updated 2 Dec 2025
Brief summary (registry, in English)
To evaluate the platelet function, clinical efficacy, prognosis and safety of Xuesaitong soft capsule in the treatment of acute coronary syndrome, 50 patients with acute coronary syndrome after PCI were treated with Xuesaitong soft capsule (mainly Panax notoginseng saponins) for 4 weeks. The macroscopic and microscopic characterization and biological basis of Xuesaitong soft capsule in the treatment of acute coronary syndrome were explained by multi-group techniques (platelet transcription group, metabolic group, protein group).
- Status (registry)
- Completed
- Phase (registry)
- Phase 1/2
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 28 Jun 2024
- Start date
- 23 Dec 2024
- Primary completion date
- 2 Nov 2025
- Lead sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
- Diseases
- Coronary artery disease
- NCT number
- NCT06618495
What you commit to
- Study type: Interventional · Phase 1/2
- Participants enrolled: 60
- From 23 Dec 2024 to the primary completion date, 2 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- (1) uncontrollable hypertension after drug treatment (systolic blood pressure \> 180mmHg, or diastolic blood pressure \> 110mmHg).
- (2) increased risk of bleeding: previous history of hemorrhagic stroke; intracranial aneurysms; trauma or major surgery within 1 month (including bypass surgery); diseases currently suffering from active bleeding, etc.
- (3) patients with history of digestive tract ulcer and massive gastrointestinal bleeding.
- (4) severe organic heart disease, such as patients with LVEF \< 35% or NYHA/Killip cardiac function grade IV.
- (5) those with a history of malignant arrhythmias (arrhythmias affected by hemodynamics, requiring drug or electrical cardioversion, or cardiopulmonary resuscitation), congenital heart disease or malignant tumor were considered unable to participate in the trial.
- (6) severe hepatic and renal insufficiency: glutamic pyruvic transaminase (ALT) or aspartate oxaloacetic transaminase (AST) ≥ 3 × normal upper limit (ULN) or total bilirubin (TBIL) ≥ 2 × ULN; or creatinine clearance (Ccr \< 30ml/min).
- (7) Women in pregnancy (defined as positive blood pregnancy test) and lactating women.
- (8) those with a history of blood donation or significant blood loss in the last 3 months (≥ 400ml).
- (9) people with a previous history of alcoholism (i.e. men drink more than 28 standard units per week and women drink more than 21 standard units per week (1 standard unit contains 14g alcohol, such as 360mL beer or 25mL spirits or 150mL wine with 40% alcohol content); or screen those who drink regularly in the first 6 months (that is, more than 14 standard units per week).
- (10) those with a history of drug abuse and drug dependence within one year before screening.
- (11) those who have participated in other clinical trials and taken trial drugs in the past 3 months.
- (12) people who are allergic or intolerant to aspirin or P2Y12 receptor inhibitors.
- (13) those who are allergic to the ingredients of the test drugs.
- (14) other situations in which the researchers think it is not appropriate to participate in this experiment.
Who the study is looking for
- (1) it accords with the diagnostic criteria of western medicine for acute coronary syndrome.
- (2) within 4 weeks after coronary intervention.
- (3) 18 years old ≤ age ≤ 80 years old, male or female.
- (4) voluntarily participate in this clinical trial, give informed consent and sign an informed consent form
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.