NCT06619093Not yet recruiting
Relationship Between Biological Phenotype, Clinical Severity of Sickle Cell Disease, and Blood Coagulation
Source: ClinicalTrials.gov · Last updated 15 Jan 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Sickle cell disease is characterized by chronic hemolytic anemia and blood rheological alterations. In addition, blood coagulation abnormalities have been reported in patients with sickle cell disease and hemolysis-derived products could be involved. The investigators hypothesized that patients with sickle cell disease and severe hemolysis (Lactate Dehydrogenase level \> 484 IU/L) could have an increased risk of hypercoagulable state and subsequent thromboembolic complications.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 26 Sept 2024
- Start date
- 1 Feb 2025
- Primary completion date
- 1 Feb 2028
- Lead sponsor
- Hospices Civils de Lyon
- Diseases
- Sickle cell disease
- NCT number
- NCT06619093
What you commit to
- Study type: Observational
- Planned participants: 200
- From 1 Feb 2025 to the primary completion date, 1 Feb 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patient who has undergone a transfusion or therapeutic phlebotomy within the 3 months prior to inclusion
Other
- Patient participating in another interventional research protocol that may interfere with the present protocol (at the investigator\'s discretion)
- Patient under guardianship, curatorship, or legal protection
- Patient subject to a legal protection measure
- Person admitted to a health or social care institution for purposes other than research
Who the study is looking for
- Aged 8 years or older
- Under clinical follow-up for a diagnosis of sickle cell disease, specifically genotypes S/S, S/beta0, or S/C
- Patient covered by a social security or equivalent health insurance plan
- Collection of the non-opposition for adults
- Information of the minor and collection of the non-opposition from both parents
Age in the registry: 8 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Service de Médecine Interne - Hôpital Edouard Herriot Coordinator of this site? Confirm its status | Lyon | France | Unknown status |
| Insitut Hématologique et Oncologique Pédiatrique (IHOPe) Coordinator of this site? Confirm its status | Lyon | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.