NCT06620523RecruitingPhase 2
Prevent Cardiac Surgery Associated AKI Trial
Efficacy of Mitochondrial Directed Therapy in Prevention of Cardiac Surgery Associated AKI Prevent Cardiac Surgery Associated AKI Trial (Prevent CSA-AKI Trial)
Source: ClinicalTrials.gov · Last updated 14 Oct 2026
Brief summary (registry, in English)
Prevent CSA-AKI (Cardiac Surgery Associated Acute Kidney Injury) trial is a double blinded randomized controlled trial, 242 patients undergoing elective cardiopulmonary bypass surgery (CPB)will either receive a placebo or daily 1200 mg of Co enzyme Q10 (CoQ10) and 1000 mg of Glutathione (GSH), the first dose will be given the day before surgery and continues while admitted up to 1 week. Blood and urine samples will be collected. Adverse events related to the study drugs will be collected.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 242 (estimated)
- First submitted
- 30 Jul 2024
- Start date
- 18 Jul 2024
- Primary completion date
- 17 Jun 2027
- Lead sponsor
- George Washington University
- Diseases
- Coronary artery disease
- NCT number
- NCT06620523
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 242
- From 18 Jul 2024 to the primary completion date, 17 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Status post-kidney transplant
Other illness
- Allergy to CoQ10
- Allergy to Glutathione
- Allergy to Cellulose
Lab values
- GFR (Glomerular Filtration Rate) \<45 ml/min
Other
- Solitary kidney
- Pregnant women
Who the study is looking for
- Adult 18-70 years of age
- Undergoing elective CPB (Cardiopulmonary Bypass) surgery
- Baseline GFR (Glomerular Filtration Rate) ≥45 ml/min
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| George Washington University Hospital Coordinator of this site? Confirm its status | Washington D.C. | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.