NCT06621264Recruiting
Exercise Activity to Improve Mobility in Patients With CKD and PAD
EXercise ACTivity to Improve Mobility, Active Behavior and Quality of Life of Chronic Kidney Disease Patients With Peripheral Artery Disease: the EXACTckd-pad Multicenter Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 31 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
People affected by chronic kidney disease and concomitant diagnosed peripheral artery disease at intermediate stages, without contraindications to exercise therapy will be invited to participate in the study. Whose providing informed consent, will be randomly assigned to one of two groups: 1. Exercise program receiving two daily 10-minute interval walking sessions at a slow increasing speed. 2. Control group: receiving usual care including optimal medical therapy and nutritional advice. Patients of both groups will be measured at baseline, after the end of the exercise program (6-month) and at follow up (12-month). Outcome measures will include walking ability by the 6-minute walking test (primary outcome) and lower limbs perfusion, body composition, quality of life, laboratory outcomes and long-term hospitalizations.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 124 (estimated)
- First submitted
- 26 Sept 2024
- Start date
- 1 Oct 2024
- Primary completion date
- 20 Nov 2025
- Lead sponsor
- University Hospital of Ferrara
- Diseases
- Chronic kidney disease
- NCT number
- NCT06621264
What you commit to
- Study type: Interventional
- Planned participants: 124
- From 1 Oct 2024 to the primary completion date, 20 Nov 2025
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- major surgery planned in the next 3 months;
Other illness
- known comorbid conditions that may limit survival to less than 2 years;
Other
- major amputations;
- inability or unwillingness to comply with protocol requirements.
Who the study is looking for
- chronic kidney disease at KDOQI stages III or IV and concomitant Peripheral artery disease at stages I, II, III;
- ability to walk independently;
- cognitive function to give informed consent identified by a Mini Mental Status Examination score greater or equal to 20/30
- absence of clinical conditions contraindicating exercise therapy (e.g., unstable angina, severe heart failure at NYHA class IV, anemia with lower than 10.0 g/dl).
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Of Ferrara Coordinator of this site? Confirm its status | Ferrara | Italy | Recruiting |
| Ospedale Pederzoli Peschiera del Garda Coordinator of this site? Confirm its status | Peschiera del Garda | Italy | Recruiting |
| Grande Ospedale Metropolitano Bianchi Melacrino Morelli Coordinator of this site? Confirm its status | Reggio Calabria | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.