NCT06622941RecruitingPhase 2
Study to ONO-4538 in Patients With Rhabdoid Tumor
A Multicenter, Open-label, Uncontrolled Phase II Study to Investigate Efficacy and Safety of ONO4538 in Patients With Rhabdoid Tumor
Source: ClinicalTrials.gov · Last updated 4 Aug 2026
Brief summary (registry, in English)
Investigate the efficacy and safety of ONO-4538 for the treatment of rhabdoid Tumors
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 23 (estimated)
- First submitted
- 30 Sept 2024
- Start date
- 25 Nov 2024
- Primary completion date
- 31 Jan 2029
- Lead sponsor
- Ono Pharmaceutical Co., Ltd.
- Diseases
- Childhood cancers
- NCT number
- NCT06622941
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 23
- From 25 Nov 2024 to the primary completion date, 31 Jan 2029
- 14 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with a history of active concurrent malignancy or complications
- Patients with spinal lesions expected to require radiation therapy or surgical intervention during the trial period
- Patients with concomitant central nervous system disorders other than AT/RT that are inadequately controlled or may lead to discontinuation of the investigational drug
Who the study is looking for
- Gender: Not specified
- Age (at the time of consent): 1 year or older
- Patients who are refractory or intolerant to one or more regimens of chemotherapy for rhabdoid Tumors
- Patients with advanced or recurrent rhabdoid Tumors not eligible for curative resection
Age in the registry: 1 year to - · Sex: All · Does not accept healthy volunteers
Sites (14)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chiba University Hospital Coordinator of this site? Confirm its status | Chiba | Japan | Recruiting |
| National Cancer Center Hospital Coordinator of this site? Confirm its status | Chuo Ku | Japan | Recruiting |
| Kyushu University Hospital Coordinator of this site? Confirm its status | Fukuoka | Japan | Not yet recruiting |
| Fukushima Medical University Hospital Coordinator of this site? Confirm its status | Fukushima | Japan | Recruiting |
| Hiroshima University Hospital Coordinator of this site? Confirm its status | Hiroshima | Japan | Recruiting |
| Kanazawa University Hospital Coordinator of this site? Confirm its status | Kanazawa | Japan | Recruiting |
| Hyogo Prefectural Kobe Children's Hospital Coordinator of this site? Confirm its status | Kobe | Japan | Recruiting |
| University Hospital Kyoto Prefectural University of Medicine Coordinator of this site? Confirm its status | Kyoto | Japan | Recruiting |
| Tohoku University Hospital Coordinator of this site? Confirm its status | Miyagi | Japan | Recruiting |
| Nagoya University Hospital Coordinator of this site? Confirm its status | Nagoya | Japan | Recruiting |
| Niigata University Medical & Dental Hospital Coordinator of this site? Confirm its status | Niigata | Japan | Recruiting |
| Osaka City General Hospital Coordinator of this site? Confirm its status | Osaka | Japan | Recruiting |
| Hokkaido University Hospital Coordinator of this site? Confirm its status | Sapporo | Japan | Recruiting |
| National Center for Child Health and Development Coordinator of this site? Confirm its status | Tokyo | Japan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.