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NCT06625762Recruiting

Nantes Bariatric Surgery Cohort

Source: ClinicalTrials.gov · Last updated 3 Apr 2026

Brief summary (registry, in English)

While current research suggests that inflammation of adipose tissue in obesity is linked to accelerated aging, it has yet to be determined in humans how this could enhance preventative and personalized medicine for obese individuals. The NBC study aims to investigate : 1. Whether bariatric surgery is associated with changes in biological age 2. If bariatric surgery alters adipocyte dysfunction, the microbiota and biological rhythms 3. Whether changes in adipocyte dysfunction, microbiota and biological rhythms are linked to changes in biological age. To achieve this, establishing a biocollection before, during and after bariatric surgery will be crucial in addressing these questions

Status (registry)
Recruiting
Study type
Interventional
Enrollment
300 (estimated)
First submitted
3 Sept 2024
Start date
23 Mar 2026
Primary completion date
23 Mar 2028
Lead sponsor
Nantes University Hospital
Diseases
Obesity
NCT number
NCT06625762

What you commit to

  • Study type: Interventional
  • Planned participants: 300
  • From 23 Mar 2026 to the primary completion date, 23 Mar 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Persons protected by law (guardianship or trusteeship) or deprived of their freedom,
  • Pregnant women (contraindication to CB) or nursing mothers.

Who the study is looking for

  • Individuals selected for bariatric surgery (starting the BC pathway within the Nantes University Hospital bariatric unit). Inclusion criteria are those of the Bariatric Surgery program.
  • male or female, adult over 18 years of age
  • BMI ≥ 35 kg/m2 with complication(s) or ≥ 40 kg/m2 with or without complication (the list of eligible complications is referenced in HAS 2024 recommendations). In the event of a change in access to bariatric surgery, this threshold could be revised without any substantial change to the protocol.
  • having consented to their participation in the cohort
  • participant affiliated to or benefiting from a social security scheme

Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Nantes University Hospital
Coordinator of this site? Confirm its status
NantesFranceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.