NCT06625944Recruiting
Exploring How Viral Infections Affect People With Chronic Lung Disease
Prospective Cohort Study to Understand Impact of Viral Infection in Chronic Lung Disease
Source: ClinicalTrials.gov · Last updated 14 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Many people with chronic lung disease have disease flare-ups. It was previously believed that these were mainly caused by bacteria but recent evidence suggests that viruses could be an important trigger. This study will recruit volunteers with chronic lung disease and take samples both when well (at baseline) and during flare-ups (exacerbations) to better understand the role of viruses in triggering exacerbations and also how the immune response is affected. The researchers will follow the volunteers\' progress for up to two years. Whenever they get unwell they will take some samples (nose swabs, finger prick testing, phlegm sample) and post them to the researchers. Then, they will come in for a visit for more samples (blood tests, further swabs) and a review.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 180 (estimated)
- First submitted
- 1 Oct 2024
- Start date
- 1 Nov 2024
- Primary completion date
- Apr 2027
- Lead sponsor
- Imperial College London
- Diseases
- COPD
- NCT number
- NCT06625944
What you commit to
- Study type: Observational
- Planned participants: 180
- From 1 Nov 2024 to the primary completion date, Apr 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Inability to complete daily symptom diaries and/or attend for clinical assessments.
- Exacerbation within 4 weeks of study recruitment and/or clinical instability at the time of recruitment.
- Pregnancy.
Who the study is looking for
- Adults with a physician confirmed diagnosis of chronic airway disease (e.g. COPD and bronchiectasis) according to established diagnostic criteria.
- AND
- \- Prior history of exacerbation within last year (defined as requiring antibiotic and/or corticosteroids).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Royal Brompton Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.