NCT06626022RecruitingPhase 3
Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.
A Phase 3, Multicenter, International, Non-inferiority, Randomized Clinical Trial Comparing Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging (MUSIC-Screen)
Source: ClinicalTrials.gov · Last updated 25 Sept 2026
Brief summary (registry, in English)
The purpose of this study is to compare whether the FDA and Health Canada approved microUS is as effective as the currently used option (MRI) for imaging the prostate gland. Participants will be randomized into two groups to compare the imaging results of the current standard of care MRI and the new microUS. The study is looking to identify the most effective imaging modality to help guide whether you progress to have a prostate biopsy.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 1284 (estimated)
- First submitted
- 1 Oct 2024
- Start date
- 8 May 2025
- Primary completion date
- 30 Nov 2029
- Lead sponsor
- University of Alberta
- Diseases
- Prostate cancer
- NCT number
- NCT06626022
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 1284
- From 8 May 2025 to the primary completion date, 30 Nov 2029
- 9 sites in 5 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior personal history of prostate cancer;
- Prior prostate imaging using microUS or MRI;
- Testosterone replacement therapy within last 12 months; or
- Androgen deprivation therapy within last 12 months.
Other
- Contraindication to microUS or MRI;
Who the study is looking for
- Male sex;
- Age 50-70;
- PSA 3-20 and/or abnormal DRE;
- Biopsy naïve.
Age in the registry: 50 years to 70 years · Sex: Male · Accepts healthy volunteers
Sites (9)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Alberta Coordinator of this site? Confirm its status | Edmonton | Canada | Active, not recruiting |
| CIUSSS du Nord-de-L'Ile-De-Montreal Coordinator of this site? Confirm its status | Montreal | Canada | Not yet recruiting |
| Sunnybrook Health Sciences Centre Coordinator of this site? Confirm its status | Toronto | Canada | Recruiting |
| University of British Columbia Coordinator of this site? Confirm its status | Vancouver | Canada | Recruiting |
| Urologia Clinica Bilbao Coordinator of this site? Confirm its status | Bilbao | Spain | Recruiting |
| CH de Martigues Coordinator of this site? Confirm its status | Martigues | France | Recruiting |
| Vestfold Hospital Trust Coordinator of this site? Confirm its status | Tønsberg | Norway | Recruiting |
| UT Southwestern Medical Center Coordinator of this site? Confirm its status | Dallas | United States | Not yet recruiting |
| University of California Los Angeles (UCLA). Coordinator of this site? Confirm its status | Los Angeles | United States | Recruiting |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.