NCT06626165CompletedPhase 4
Association Between Effectiveness of Mirikizumab and UC Patients With High Neutrophilic Infiltration in Epithelium of the Colonic Mucosa
Mirikizumab Therapy is Effective for Patients With Moderate to Severe Ulcerative Colitis Patients Whose Geboes Score Grade is ≥3.2) on Endoscopic Biopsy
Source: ClinicalTrials.gov · Last updated 20 Oct 2025
Brief summary (registry, in English)
The goal of this study is to confirm that Mirikizumab therapy may provide clinical, endoscopic, and histopathologic improvements in patients with moderate to severe UC refractory to maintenance therapy when high neutrophilic infiltration in epithelium of the colonic mucosa (Geboes score Grade ≥3.2) on endoscopic biopsy is found.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 100 (actual)
- First submitted
- 20 Jul 2024
- Start date
- 20 Jul 2024
- Primary completion date
- 30 Sept 2025
- Lead sponsor
- Showa Inan General Hospital
- Diseases
- Ulcerative colitis
- NCT number
- NCT06626165
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 100
- From 20 Jul 2024 to the primary completion date, 30 Sept 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- the presence of a long-term illness, colorectal cancer, or infectious colitis
Who the study is looking for
- They were endoscopically active ulcerative colitis patients.
Age in the registry: 19 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Showa Inan General Hospital Coordinator of this site? Confirm its status | Komagane | Japan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.