NCT06633224Recruiting
Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT
An Evaluation of Changes in the Relationships Between Fatigue and Molecular Mechanisms in Cancer Patients Receiving Curative-Intent Combined Chemotherapy and Radiation Therapy (CCRT)
Source: ClinicalTrials.gov · Last updated 15 Sept 2026
Brief summary (registry, in English)
Cancer-related fatigue (CRF) is a significant problem for cancer patients. This prospective, basic science, observational study will evaluate for changes in CRF associated with molecular characteristics prior to, during, and at the completion of non-investigational, standard-of-care, combined chemotherapy and radiation therapy (CCRT) and to develop and assess predictive models for CRF severity.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 125 (estimated)
- First submitted
- 7 Oct 2024
- Start date
- 27 Dec 2024
- Primary completion date
- 1 Feb 2027
- Lead sponsor
- University of California, San Francisco
- Diseases
- Head and neck cancer
- NCT number
- NCT06633224
What you commit to
- Study type: Observational
- Planned participants: 125
- From 27 Dec 2024 to the primary completion date, 1 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Contraindication to phlebotomy for removal of approximately 50 mL of peripheral blood within 6 week period (Institutional Review Board (IRB) limit).
Who the study is looking for
- Participants have not received any prior treatment (i.e., cancer systemic therapies or radiation therapy) in the month except surgery or inductive Chemotherapy (CTX).
- Participants receiving \>= 15 fractions.
- Participants is male or female and is \>18 years of age on the day of signing the informed consent.
- Ability to understand a written informed consent document.
- Able and willing to complete all of the study questionnaires and provide blood and stool samples prior to, midway, and following the completion of treatment.
- Willing to have medical records reviewed for clinical information.
- Able to read, write and understand English or Spanish.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.