NCT06634979Recruiting
Selective Lymph Node Resection for Invasive Non-small Cell Lung Cancer With the CTR of 0.5-1 and the Diameter of ≤ 2 cm
Selective Lymph Node Resection for Invasive Non-small Cell Lung Cancer With the CTR of 0.5-1 and the Diameter of ≤ 2 cm: a Prospective， Single-arm, Multi-center, Phase Ⅱ Trial
Source: ClinicalTrials.gov · Last updated 12 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The study investigated the efficacy and safety of a selective lymph node strategy (no lower mediastinal lymph node dissection for upper lobe tumors and no upper mediastinal lymph node dissection for lower lobe tumors) in patients with 0.5 \< CTR \< 1 and ≤ 2 cm in diameter cT1N0M0 infiltrating NSCLC, aiming to more accurately assess the prognosis of the selective lymph node dissection strategy for nodes with 0.5 \< CTR \< 1 and ≤ 2 cm in diameter.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 684 (estimated)
- First submitted
- 8 Oct 2024
- Start date
- 1 May 2024
- Primary completion date
- 1 May 2026
- Lead sponsor
- Fudan University
- Diseases
- Lung cancer
- NCT number
- NCT06634979
What you commit to
- Study type: Interventional
- Planned participants: 684
- From 1 May 2024 to the primary completion date, 1 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Inability to perform complete surgical resection;
- Previous surgery for lung cancer;
- Patients who have received radiotherapy or chemotherapy for non-primary treatment.
Other illness
- cytology or histopathology confirms that it is a lung malignant tumor other than non-small cell lung cancer;
Other
- T1N0M0 with a clinical stage other than 0.5 \< CTR \< 1 and a diameter of ≤ 2 cm;
Who the study is looking for
- Volunteer to participate in a clinical study and be willing to follow and have the ability to complete all trial procedures;
- Age 18-80 years at time of signing informed consent (including threshold);
- ECOG score 0 or 1;
- No previous surgery for lung cancer;
- Intraoperative or postoperative pathologically confirmed non-small cell lung cancer;
- Single pulmonary nodule with mixed ground glass on CT, or multiple pulmonary nodules but the main lesion is the above nodules;
- The proportion of solid components of the nodule is between 0.5 and 1, and the total size of the nodule is less than or equal to 2 cm;
- Patients with clinical stage T1N0M0 surgically resectable;
- Primary treatment without radiotherapy or chemotherapy.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fudan University Shanghai Cancer Center Coordinator of this site? Confirm its status | Shanghai | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.