NCT06635525Recruiting
Impact Of Kidney Failure On The Regulation Of Humoral Response To Vaccination
Source: ClinicalTrials.gov · Last updated 30 Mar 2026
Brief summary (registry, in English)
The aim of this observational study is to determine if and how kidney failure affects the development of protective immune responses following vaccination in patients on chronic dialysis. Researchers will compare the effectiveness of the influenza vaccine in inducing protective antibodies between hemodialysis patients and subjects without chronic kidney disease. Participants will: * Be enrolled at the time of influenza vaccination * Visit the clinic at 7, 14, 30, 60, and 120 days after vaccination * Be asked to provide relevant clinical information and a blood sample at each visit
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 146 (estimated)
- First submitted
- 8 Oct 2024
- Start date
- 16 Oct 2024
- Primary completion date
- Jul 2026
- Lead sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
- Diseases
- Chronic kidney disease
- NCT number
- NCT06635525
What you commit to
- Study type: Observational
- Planned participants: 146
- From 16 Oct 2024 to the primary completion date, Jul 2026
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Administration of immunosuppressive drugs in the two weeks prior to vaccination.
- Administration of another vaccine in the three weeks prior to enrollment (co-administration of other vaccines with those under study does not contraindicate participation).
- Systemic infection clinically resolved less than two weeks before enrollment.
Other illness
- Recent influenza infection (clinically resolved less than 3 months ago).
Who the study is looking for
- Age between 18 and 70 years
- Patients undergoing thrice-weekly hemodialysis / peritoneal dialysis for at least 3 months OR healthy individuals without a history of renal insufficiency
- Subjects eligible to receive a seasonal influenza vaccine
- Signed informed consent for participation in the study
Age in the registry: 18 years to 70 years · Sex: All · Accepts healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Coordinator of this site? Confirm its status | Milan | Italy | Recruiting |
| Asst Santi Paolo E Carlo Coordinator of this site? Confirm its status | Milan | Italy | Not yet recruiting |
| ASST Fatebenefratelli Sacco Coordinator of this site? Confirm its status | Milan | Italy | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.