NCT06636487Active, not recruiting
Expand Pulmonary Rehabilitation to Other Chronic Respiratory Diseases Than COPD
Expanding Pulmonary Rehabilitation in Other Chronic Respiratory Disease Than COPD - the ExPuRe Pilot Study
Source: ClinicalTrials.gov · Last updated 9 Mar 2026
Brief summary (registry, in English)
The purpose of this pilot randomized clinical trial is to evaluate the willingness, acceptance, adherence and signs of benefits of structured home-based pulmonary rehabilitation (HPR) and supervised pulmonary tele-rehabilitation (PTR) on respiratory symptoms, quality of life, functioning and physical activity in patients with ILD (Interstitial lung disease, Idiopathic pulmonary fibrosis, Sarcoidosis), Bronchiectasis and Asthma who have a clinically assessed need for a pulmonary rehabilitation program. The main questions the project aims to answer are: * Will HPR and PTR appeal to a minimum of 30% of the eligble patients * Be greatly accepted (≥70% of participant complete 70% or more of the planned sessions) by patients agreeing to participate in the study * Will PTR and HPR lead to positive changes in respiratory symptom relief, symptom relief in general and improve or maintain physical functioning larger than usual care Researchers will compare with a comparable control group who gets usual care (scheduled controls and medication but no exercise intervention) to examine the willingness to be randomized and to get an indication on possible health related effects. Participants will be randomly assigned to one of three groups: 1. A structured supervised group-based PTR (exercise twice a week; each session consists of 35 min. evidence-based exercises and 25 min. of patient education) 2. An individual HPR program (self-initiated physical activity) with motivational and professional counseling once a week (10-15min), supported by a tablet screen 3. A control group receiving usual care (CON)
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 50 (actual)
- First submitted
- 7 Oct 2024
- Start date
- 1 Nov 2024
- Primary completion date
- 30 Sept 2025
- Lead sponsor
- Copenhagen University Hospital, Hvidovre
- Diseases
- Idiopathic pulmonary fibrosis, Asthma
- NCT number
- NCT06636487
What you commit to
- Study type: Interventional
- Participants enrolled: 50
- From 1 Nov 2024 to the primary completion date, 30 Sept 2025
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cognitive impairment - unable to follow instructions
Other
- Impaired hearing or vision - unable to see or hear instruction from a tablet
- Unable to understand and speak Danish
- Comorbidities where the exercise content is contraindicated
Who the study is looking for
- Residency in the Capital Region of Copenhagen
- A clinically assessed need for pulmonary rehabilitation including respiratory symptoms, corresponding to MRC grade 2 or higher and where:
- Center-based PR is not standard available or
- Center-based PR being declined by the patient
- Able to stand up from a chair (height 44-46cm) and walk 10 meters independently (with or without a walking aid)
- Capable of lifting both arms to horizontal with at least 1 kg dumbbells in each hand
- And a minimum of one of the below mentioned diagnoses:
- ILD (Interstitial lung disease, Idiopathic pulmonary fibrosis, Sarcoidosis):
- DLCO lower than 80 % or FVC lower than 80%, HRCT verified, Age higher than 40 years, Confirmed respiratory physician diagnosis
- Asthma:
- With chronic airway obstruction, ACQ score higher than 1, FEV1 lower than 80%, Age higher than 50 years, Confirmed respiratory physician diagnosis of Asthma
- Bronchiectasis:
- FEV1 lower than 80%, HRCT verified, Age higher than 40 years, Confirmed respiratory physician diagnosis
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Copenhagen University Center, Amager Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Copenhagen University Center, Frederiksberg-Bispebjerg Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Copenhagen University Center, Hvidovre Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Copenhagen University Center, Herlev-Gentofte Coordinator of this site? Confirm its status | Gentofte Municipality | Denmark | Unknown status |
| Copenhagen University Center, Hillerød Coordinator of this site? Confirm its status | Hillerød | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.