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NCT06638957Completed

Impact of the COVID-19 Pandemic on Oncologic Outcomes in Colorectal Cancer

Impact of the Coronavirus Disease 2019 Pandemic on Oncologic Outcomes in Colorectal Cancer

Source: ClinicalTrials.gov · Last updated 15 Oct 2024

Brief summary (registry, in English)

The goal of this observational study is to assess the impact of the COVID-19 pandemic on colorectal cancer (CRC) outcomes, particularly focusing on stage distribution and recurrence-free survival in patients undergoing surgery at eight tertiary care institutions in Korea from 2018 to 2020. Main Question Does the COVID-19 pandemic lead to more advanced stages of colorectal cancer at diagnosis and higher complication rates during surgery? Is there a significant difference in recurrence-free survival between CRC patients treated before and during the pandemic? This study found that more patients presented with advanced-stage CRC during the COVID-19 pandemic, with significantly higher rates of tumor-related complications (perforations, abscesses, and preoperative obstructions), as well as an increase in open surgeries and combined resections. No significant difference in recurrence-free survival was observed between the pre-COVID-19 and COVID-19 periods, although postoperative complication rates were higher, especially among rectal cancer patients and those receiving preoperative chemoradiotherapy.

Status (registry)
Completed
Study type
Observational
Enrollment
14951 (actual)
First submitted
7 Oct 2024
Start date
1 Jan 2018
Primary completion date
31 Dec 2020
Lead sponsor
In Ja Park
NCT number
NCT06638957

What you commit to

  • Study type: Observational
  • Participants enrolled: 14951
  • From 1 Jan 2018 to the primary completion date, 31 Dec 2020
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study design.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Hereditary non-polyposis colon cancer (HNPCC)
  • Cancer associated with inflammatory bowel disease (IBD)
  • Colorectal cancer not proven on biopsy, and pathologies other than adenocarcinoma.

Other

  • Familial adenomatous polyposis (FAP)
  • Emergency operation

Who the study is looking for

  • Patients diagnosed with colorectal cancer who underwent surgery
  • in 8 institution including Asan Medical Center, Seoul St. Mary's Hospital, Korea University Anam Hospital, Samsung Medical Center, Pusan National University Yangsan Hospital, Gangnam Severance Hospital, Kyungpook National University Chilgok Hospital, and Chonnam National University Hwasun Hospital

Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Asan Medical Center
Coordinator of this site? Confirm its status
SeoulSouth KoreaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.