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NCT06639360Recruiting

Effects of Transcranial Magnetic Stimulation After Endovascular Treatment for Acute Ischemic Stroke

Source: ClinicalTrials.gov · Last updated 4 Dec 2025

Brief summary (registry, in English)

This is a multicenter, randomized, double-blind, sham-controlled trial, to determine the efficacy and safety of cTBS in treating patients with acute ischemic stroke after endovascular treatment.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
60 (estimated)
First submitted
10 Oct 2024
Start date
2 Aug 2025
Primary completion date
30 Sept 2026
Lead sponsor
Xijing Hospital
Diseases
Stroke
NCT number
NCT06639360

What you commit to

  • Study type: Interventional
  • Planned participants: 60
  • From 2 Aug 2025 to the primary completion date, 30 Sept 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients with contraindications to TMS treatment, such as those with metallic foreign objects in the head, pacemakers, implantable drug pumps, cochlear implants, etc.;
  • Head CT/MRI indicates midline shift or significant mass effect, or patients planned for surgical intervention;
  • Patients who are participating in other interventional clinical studies within 30 days before the start of this study or after the onset of this condition;

Other illness

  • Patients with epilepsy, increased intracranial pressure, tumors, acute cerebral hemorrhage, or other severe neurological diseases, and those with severe functional impairment of organs such as the heart, liver, and kidneys;
  • Patients with severe mental disorders or dementia who cannot cooperate with follow-up;
  • Patients with other severe diseases resulting in an expected survival of less than 90 days;

Other

  • Head CT/MRI suggests acute cerebral infarction in both sides;
  • Patients who are pregnant or breastfeeding;
  • Patients who cannot cooperate with informed consent.

Who the study is looking for

  • Patients with acute anterior circulation ischemic stroke aged between 18 and 80 years old.
  • Imaging suggests that the infarction is caused by occlusion of the terminal portion of the internal carotid artery or the M1/M2 segment of the middle cerebral artery.
  • A head CT within 24 hours of onset indicates an ASPECT score ≥6, and meets the guideline-recommended criteria for thrombectomy.
  • Pre-stroke mRS score is ≤1.
  • NIHSS score before thrombectomy is between 6 and 25.
  • With vascular recanalization of mTICI \> 2b/3.
  • Informed consent form signed.

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Xijing hospital
Coordinator of this site? Confirm its status
Xi'anChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.