NCT06641297Recruiting
White Matter Plasticity in Schizophrenia
Source: ClinicalTrials.gov · Last updated 20 Feb 2026
Brief summary (registry, in English)
Schizophrenia spectrum disorders are associated with impairment in the microstructure of white matter, the key brain tissue responsible for fast communication between different brain regions necessary for any complex task. This white matter impairment is linked to problems with cognition in schizophrenia, especially slower processing speed. This project aims to study the potential for correcting white matter deficits in schizophrenia by examining mechanisms underlying white matter structure changes in response to training on playing a mock musical instrument.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 36 (estimated)
- First submitted
- 11 Oct 2024
- Start date
- 2 Jan 2025
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- University of Maryland, Baltimore
- Diseases
- Schizophrenia
- NCT number
- NCT06641297
What you commit to
- Study type: Interventional
- Planned participants: 36
- From 2 Jan 2025 to the primary completion date, 31 Dec 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- contraindications to MRI (metal implants, claustrophobia)
Other illness
- medical condition that limits use of hands (ie, arthritis)
- Active or recent (within 6 months) substance use disorder other than nicotine
Who the study is looking for
- Diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder, or psychosis NOS
- age 15-45
- able to provide informed consent
Age in the registry: 15 years to 45 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Maryland Baltimore - Maryland Psychiatric Research Center Coordinator of this site? Confirm its status | Catonsville | United States | Not yet recruiting |
| Maryland Psychiatric Research Center Coordinator of this site? Confirm its status | Catonsville | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.