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NCT06643299CompletedPhase 2

Probiotic Use for Recovery Enhancement From Long COVID-19

PURE-LC - Probiotic Use for Recovery Enhancement From Long COVID

Source: ClinicalTrials.gov · Last updated 7 Aug 2026

Brief summary (registry, in English)

The goal of this clinical trial is to learn if probiotics can improve symptoms and quality of life in participants with Long COVID.

Status (registry)
Completed
Phase (registry)
Phase 2
Study type
Interventional
Enrollment
194 (actual)
First submitted
14 Oct 2024
Start date
13 May 2025
Primary completion date
2 Jul 2026
Lead sponsor
Rush University Medical Center
NCT number
NCT06643299

What you commit to

  • Study type: Interventional · Phase 2
  • Participants enrolled: 194
  • From 13 May 2025 to the primary completion date, 2 Jul 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Are unable to take the study medication daily
  • Are currently taking immunosuppressants

Other illness

  • Have been diagnosed with an immune-compromising condition
  • Are enrolled in another Long COVID study with an intervention

Other

  • No longer have symptoms consistent with LC
  • Are currently pregnant or planning to become pregnant over the course of the study
  • Are currently breastfeeding
  • Do not speak English as a primary language
  • Are regularly taking probiotics

Who the study is looking for

  • Age ≥18 years who report Long COVID with persistent symptoms at the time of study initiation

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Rush University Medical Center
Coordinator of this site? Confirm its status
ChicagoUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.