NCT06647602Not yet recruiting
Thyroid Hormone Replacement After Radio Iodine: Value and Efficacy
Source: ClinicalTrials.gov · Last updated 10 Feb 2026
Brief summary (registry, in English)
This study will be a multicentre prospective cohort study on TH-substitution after thyroid hormone withdrawal preceding radioiodine treatment.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 40 (estimated)
- First submitted
- 11 Jun 2024
- Start date
- 1 Sept 2026
- Primary completion date
- 31 Mar 2028
- Lead sponsor
- University Medical Center Groningen
- Diseases
- Thyroid cancer
- NCT number
- NCT06647602
- EU CT number
- 2024-511668-10-00
What you commit to
- Study type: Observational
- Planned participants: 40
- From 1 Sept 2026 to the primary completion date, 31 Mar 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients using proton-pomp inhibitors
Other illness
- Patients with comorbidities, such as severe heart failure, (poorly controlled) atrial fibrillation, of which the treating physician decides that L-T3 is unsuitable.
- Conditions or drugs interfering with thyroid hormone uptake:
- Patients with a history of atrophic gastritis
Other
- Pregnancy
Who the study is looking for
- Histologically confirmed DTC (papillary thyroid carcinoma, follicular thyroid carcinoma, oncocytic thyroid carcinoma)
- Classified as high-risk DTC according to the ATA guidelines or, patients for whom the risk of a recurrence is estimated to be higher based on clinical features (assessed by their treating physician).
- Prepared for RAI-therapy with TH-withdrawal
- Patients must be fit to adhere to the study protocol
- Patients must be able to read and understand the Dutch language
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Medical Center Groningen (UMCG) Coordinator of this site? Confirm its status | Groningen | Netherlands | Unknown status |
| Radboud University Nijmegen Coordinator of this site? Confirm its status | Nijmegen | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.