A Prospective Multicenter Clinical Study： IntracOronary neaR-Infrared Spectroscopy and OptIcal Coherence Tomography for Evaluating Coronary vulNerable Plaque in Patients With diabeTes

Lab values

• 1: Severe coagulation dysfunction (APTT greater than 3 times the upper limit of the normal range)
  • 2: Severe hemodynamic disorder or shock that cannot be corrected
  • 3: Patients with renal impairment（eGFR\<30 mL/min/1.73m2）
  • 4: Severe symptoms of heart failure (NYHA III and above) or left ventricular ejection fraction \<30%
  • 5: The presence or suspected presence of infective endocarditis or systemic active infection
  • 6: Patients with refractory ventricular arrhythmias who have previously undergone coronary bypass transplantation (CABG) or plan to undergo CABG during the study
  • 7: Patients with serious concurrent diseases such as advanced cancer have a life expectancy of less than 24 months
  • 8: Pregnant or lactating women, have a family plan within 24 months or are unwilling to take effective contraceptive measures
  • 9: The target vessel has severe calcification or severe tortuosity, which cannot be examined by OCT
  • 10: Have participated in other clinical trials or are participating in other drug/device clinical trials within 3 months prior to enrollment and have not met the primary endpoint
  • 11: Investigators believe that those who are unnecessary for OCT or not suitable for inclusion in this trial.
  • 12: There are multiple lesions in the same blood vessel, and the non-target lesion distance requiring treatment vascular segment is less than 5mm

• 18 years old or older, gender is not limited
• Patients with diabetes who require an OCT examination or treatment under OCT guidance (diabetes definition: active treatment with insulin or oral hypoglycemic agents at admission). For patients with diabetes who are treated with diet only, abnormal fasting blood sugar (\>7 mmol/l), blood sugar \>11.1 mmol/l at any time, or abnormal glucose tolerance tests based on World Health Organization standards need to be recorded.
• Be able to understand the purpose of clinical research, voluntarily participate can complete the observation as required and sign the informed consent form
  • 5: Lesion stenosis greater than or equal to 50% without interventional treatment
  • 6: The diameter of the blood vessel in the diseased segment is greater than or equal to 2.5 mm