NCT06650150Completed
Respiratory Muscle Strength and Exercise Capacity in Smokers
Comparative Study on Respiratory Muscle Strength and Exercise Capacity in Smokers With COPD, PRISm and Pre-COPD
Source: ClinicalTrials.gov · Last updated 8 Aug 2025
Brief summary (registry, in English)
This cross-sectional study aims to evaluate the respiratory muscle strength and physical capacity of symptomatic adult smokers in Muğla. The study population will be the patients who were admitted to the pulmonary outpatient clinic of Muğla Training and Research Hospital between July 2024 and December 2024. The primary outcome is the proportion of individuals with Maximum Inspiratory Pressure (MIP) below 80%. Secondary outcomes include the 6-Minute Walk Test (6MWT) distance, Maximum Expiratory Pressure (MEP), and COPD Assessment Test (CAT) scores. Smokers will be categorized into COPD, PRISm, and Pre-COPD groups. The study will adjust for BMI as a key confounder and assess the modifying effects of gender, smoking habits, and age. Ethical approval and informed consent will be obtained, with data analysis focusing on descriptive statistics, comparative analysis, and regression models to understand the impact of smoking on respiratory health.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 150 (actual)
- First submitted
- 11 Oct 2024
- Start date
- 20 Oct 2024
- Primary completion date
- 20 Jul 2025
- Lead sponsor
- Muğla Sıtkı Koçman University
- Diseases
- COPD
- NCT number
- NCT06650150
What you commit to
- Study type: Observational
- Participants enrolled: 150
- From 20 Oct 2024 to the primary completion date, 20 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Respiratory infection at the time of measurement (upper or lower resp. tract, viral or bacterial infections)
- Presence of chronic respiratory diseases (Asthma, IPF, Bronchiectasis, \[except COPD\])
- Exacerbation due to chronic respiratory diseases (except mild COPD exacerbation)
- Neuromuscular disease (ALS, Guillain-Bare syndrome, Muscular dystrophies, Myasthenia gravis)
- Restrictive pulmonary disease (IPF, Sarcoidozis, Progresif Pulmonary Fibrosis)
Who the study is looking for
- At least 5 packages of cigarette smokers who have an appropriate PFT done at our lab. (pulmonary function test must be performed at evaluable standards according to ERS/ATS guidelines)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mugla Training and Research Hospital Coordinator of this site? Confirm its status | Muğla | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.