NCT06653101Completed
Effect of Akkermansia Muciniphila Akk11 on Metabolic and Gut Health in Overweight and Obese Subjects
Effect of Akkermansia Muciniphila Akk11 on Metabolic and Gut Health in Overweight and Obese Subjects: a Randomized, Double-blind, Placebo-controlled Trial
Source: ClinicalTrials.gov · Last updated 18 Nov 2025
Brief summary (registry, in English)
To assess the efficacy and safety of the use of probiotics as a food supplement compared to placebo in regulating body metabolism and gut microbiota in overweight or obese subjects.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 110 (actual)
- First submitted
- 16 Oct 2024
- Start date
- 20 Oct 2024
- Primary completion date
- 5 Dec 2024
- Lead sponsor
- Wecare Probiotics Co., Ltd.
- Diseases
- Obesity
- NCT number
- NCT06653101
What you commit to
- Study type: Interventional
- Participants enrolled: 110
- From 20 Oct 2024 to the primary completion date, 5 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recently treated with antibiotics (i.e., \< 3 months prior to the start of the study);
Other illness
- Psychiatric or neurological diseases, celiac disease, lactose intolerance, allergies;
- Have the following diseases: irritable bowel syndrome, ulcerative colitis, fatty liver, liver cirrhosis, etc.;
- It is not recommended to participate in other special circumstances, such as those who are allergic to probiotic products;
Other
- Those who have been diagnosed with high uric acid or gout are not recommended to participate in the test;
- Participants who smoked more than 10 cigarettes per day were excluded;
- Pregnant and lactating women are not suitable for experiments.
Who the study is looking for
- 18-45 years old;
- BMI ≥ 24 kg/m2 or men with a body fat percentage of ≥ 25% and women with a body fat percentage of ≥ 30%；
- Normal liver function indexes;
- Willing to complete study-related questionnaires and diaries and complete all clinical visits.
Age in the registry: 18 years to 45 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fei Xu Coordinator of this site? Confirm its status | Zhengzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.