NCT06656832Recruiting
Peripheral Drivers of Heart Failure Progression - The Prospective PEDAL-HF Study
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
PEDAL-HF is a registry-based randomized prospective multicenter study. The investigators plan to include 1000 patients who were recently admitted with acute decompensated heart failure at five tertiary heart clinics in Germany. For the randomised part, 750 patients will be randomized to care within a heart failure network or usual care. The primary endpoint of the randomized trial is change in NT-proBNP from baseline to 6 months of follow-up. All patients (randomized or not) will be followed for two years.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 1000 (estimated)
- First submitted
- 22 Oct 2024
- Start date
- 28 Nov 2024
- Primary completion date
- 1 Oct 2028
- Lead sponsor
- University of Leipzig
- Diseases
- Heart failure
- NCT number
- NCT06656832
What you commit to
- Study type: Interventional
- Planned participants: 1000
- From 28 Nov 2024 to the primary completion date, 1 Oct 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- any condition interfering with the informed consent process
Age
- Age \<18 years
Other
- pregnancy
- patients placed in an institution by official or court order
Who the study is looking for
- Patients admitted to the participating study centres with acute decompensated heart failure (ADHF), defined as clinical signs and/or symptoms of heart failure
- objective structural cardiac abnormalitites according to the ESC criteria.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Leipzig Coordinator of this site? Confirm its status | Leipzig | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.