DEBSCAN-IVL. Drug Eluting Balloon or Drug Eluting Stent to Treat CAlcified Nodules After IntraVascular Lithotripsy.

Prior treatment

• Target lesion previously treated with stents or DEB.

Other illness

• Cardiogenic Shock or Cardiac arrest at the moment of the index procedure.

Other

• Patients must not meet any criteria
• Inability to provide oral and written informed consent or unwillingness to come back for systematic angiographic follow-up.
• Pregnant or breastfeeding patients.
• Impossibility to maintain double antiplatelet treatment during at least 1 month.
• Life expectancy \<1 year.
• Index lesion at left main stem.
• Aorto-ostial lesion.
• High thrombus burden in the target lesion (TIMI thrombus scale≥3).

• Patients must meet all inclusion criteria:
• Patients \>18 years admitted for stable coronary artery disease or acute coronary syndromes and indication for percutaneous coronary intervention (PCI) and
• Severe coronary lesion with calcified nodule, confirmed with intracoronary imaging (optical coherence tomography or intravascular ultrasound) and;
• Lesion to treat in a vessel between 2.5 and 4 mm.