NCT06658795Recruiting
Treating Loneliness In The Older Adult With Depression With tDCS
Effects of Transcranial Direct Current Stimulation on Loneliness in Older Adults With Depression: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 26 Oct 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
High loneliness is prevalent among older adults and is a significant risk factor for major depression and low recovery rates in patients. Current interventions for loneliness are limited. Previous research has demonstrated a link between loneliness, negative social emotions, and reduced resting-state functional connectivity in the lateral prefrontal cortex (LPFC) and the default mode network (DMN). Transcranial direct current stimulation (tDCS) has shown promise in enhancing emotional regulation and connectivity, potentially alleviating loneliness in older adults with depression.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 180 (estimated)
- First submitted
- 22 Oct 2024
- Start date
- 29 Oct 2024
- Primary completion date
- 20 Oct 2026
- Lead sponsor
- Guangzhou Psychiatric Hospital
- Diseases
- Depression
- NCT number
- NCT06658795
What you commit to
- Study type: Interventional
- Planned participants: 180
- From 29 Oct 2024 to the primary completion date, 20 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Contraindications for tDCS or MRI (e.g., metal implants).
Other illness
- Severe neurological diseases.
- Bipolar disorder, schizophrenia, addiction, or impulse control disorders.
Other
- Presence of suicidal ideation.
Who the study is looking for
- High loneliness (UCLA Loneliness Scale \> 43).
- Diagnosis of major depressive disorder confirmed by the Structured Clinical Interview for DSM-5 Disorders.
- absence of suicidal ideation (Hamilton Depression Scale item 3 score ≤ 1).
Age in the registry: 60 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Guangzhou Brain Hospital Coordinator of this site? Confirm its status | Guangzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.