NCT06661135Completed
Open Versus Total Laparoscopic Pancreaticoduodenectomy
Total Laparoscopic Versus Open Pancreaticoduodenectomy: a Prospective Comparative Clinical Study
Source: ClinicalTrials.gov · Last updated 28 Oct 2024
Brief summary (registry, in English)
The goal of this clinical trial is to learn more about Total Laparoscopic pancreaticoduodenectomy ( TLPD ) which is performed for participants with pancreatic tumors using the laparoscope. TLPD is an operation that includes excision of the tumor with adjacent parts of the head of the pancreas, the duodenum and the part of the external biliary system . In the final step during surgery, and to reconnect the bowel after excision of the tumor, multiple anastomoses or connections will be made by the surgeon. To get valid results , the investigators performed this randomized controlled trial that compare TLPD with the traditional technique used to remove these tumors through open pancreaticoduodenectomy ( OPD ). The main questions this study aims to answer are: Is TLPD superior to open pancraticoduodenectomy ( OPD ) regarding the adequacy of surgical tumor excision ? Is TLPD lower than OPD regarding the early complications after surgery ? Researchers will compare participants receiving TLPD with participants receiving OPD regarding : The time of the operation. The amount of blood lost during surgery. Complications that may happen during or after surgery. Time of recovery after surgery. Duration to amputation. Duration of hospital stay. The adequacy of resection .
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 48 (actual)
- First submitted
- 18 Oct 2024
- Start date
- 1 Sept 2022
- Primary completion date
- 30 Dec 2023
- Lead sponsor
- Cairo University
- Diseases
- Pancreatic cancer
- NCT number
- NCT06661135
What you commit to
- Study type: Interventional
- Participants enrolled: 48
- From 1 Sept 2022 to the primary completion date, 30 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with history of previous laparotomies.
Other
- Patients who were deemed inoperable or irresectable tumors by preoperative investigations.
- Patients with complex ventral hernias.
Who the study is looking for
- Patients presenting to the outpatient clinic of Kasr Alainy Hospitals with pancreatic head tumors, duodenal tumors, ampullary, or periampullary tumors who were candidates for either open or laparoscopic pancreaticoduodenectomy
- Patients who accepted to participate in the study.
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kasralainy school of medicine , Cairo university Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
Related publications
- Laparoscopic versus open pancreatoduodenectomy: a pilot randomized trial in a developing African country.Surg Endosc · 2026 · PMID 41345531
This page is information, not medical advice. Discuss any trial with your doctor.