NCT06663163Completed
The Association Between Fever and CDKL5 Deficiency Disorder: a Nationwide Survey
Source: ClinicalTrials.gov · Last updated 14 Apr 2026
Brief summary (registry, in English)
The primary objective of this research is to study the effects of fever on seizure activity in patients with CDKL5 deficiency disorder
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 131 (actual)
- First submitted
- 27 Oct 2024
- Start date
- 29 Oct 2024
- Primary completion date
- 15 Dec 2024
- Lead sponsor
- Xuanwu Hospital, Beijing
- Diseases
- Epilepsy
- NCT number
- NCT06663163
What you commit to
- Study type: Observational
- Participants enrolled: 131
- From 29 Oct 2024 to the primary completion date, 15 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any history of previous brain disease (trauma, etc.) that likely to precipitate seizures.
Other illness
- Presence of any clinical condition that in the opinion of the principal investigator makes the patient not suitable to participate in the trial.
Who the study is looking for
- A diagnosis of CDKL5 deficiency, including molecular confirmation of a pathogenic or likely pathogenic CDKL5 variant and refractory seizures.
- Parents or guardians are willing to complete and provide information about the child's medical history and fever history after receiving the survey questionnaire online.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Xuanwu Hospital, Capital Medical University Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
Related publications
- Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications.Ann Clin Transl Neurol · 2026 · PMID 42644218
This page is information, not medical advice. Discuss any trial with your doctor.