NCT06665880Not yet recruiting
Genes, Proteins, and Metabolites in Drug-resistant Epilepsy (DRE) Patients
The Changes of Genes, Proteins, and Metabolites in Patients with Drug-resistant Epilepsy
Source: ClinicalTrials.gov · Last updated 30 Oct 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
In patients with drug-resistant epilepsy (DRE), there may be changes at the genetic, proteomic, and metabolomic levels when comparing epileptic tissues from DRE to normal tissues in traumatic brain injury (TBI). These changes could help in understanding the pathophysiological mechanisms of epilepsy and in identifying new therapeutic targets.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 16 (estimated)
- First submitted
- 5 Aug 2024
- Start date
- 15 Nov 2024
- Primary completion date
- 15 Dec 2025
- Lead sponsor
- Xuanwu Hospital, Beijing
- Diseases
- Epilepsy
- NCT number
- NCT06665880
What you commit to
- Study type: Observational
- Planned participants: 16
- From 15 Nov 2024 to the primary completion date, 15 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Severe side effects from taking antiepileptic drugs at the time of enrollment and not inappropriate for SEEG;
Other illness
- Significant heart, liver, renal insufficiency, and other medical diseases;
- A history of alcohol and drug abuse;
Other
- Progressive encephalopathy or progressive structural damage in the central nervous system;
- Significant intellectual disability;
- Any contraindication to MRI.
Who the study is looking for
- 14-60 years old, male or female, Han Chinese;
- Drug-resistant epilepsy;
- Required surgical implantation of SEEG electrodes.
Age in the registry: 14 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Xuanwu Hospital, Capital Medical University Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.