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NCT06669533Recruiting

Use Misoprostol to Optimize Prevention of Cervical Cancer

Misoprostol to Optimizing Prevention of Cancer of the Cervix: A Double-Blind Randomized Controlled Trial

Source: ClinicalTrials.gov · Last updated 5 Nov 2026

Brief summary (registry, in English)

This is a double-blind randomized controlled trial of 420 non-pregnant women undergoing cancer screening by visual inspection with acetic acid (VIA) who have Type 3 transformation zone (TZ) and randomized to receive either Misoprostol or placebo.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
840 (estimated)
First submitted
18 Oct 2024
Start date
25 Feb 2025
Primary completion date
4 Nov 2027
Lead sponsor
University of Alabama at Birmingham
NCT number
NCT06669533

What you commit to

  • Study type: Interventional
  • Planned participants: 840
  • From 25 Feb 2025 to the primary completion date, 4 Nov 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • With Type 1 or 2 TZ prior to randomization

Other illness

  • History of hysterectomy

Other

  • Currently pregnant
  • Any cancerous lesions
  • Active cervicitis

Who the study is looking for

  • Diagnosis of Type 3 TZ confirmed on exam prior to randomization
  • Age 25 years or older

Age in the registry: 25 years to - · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Cameroon Baptist Convention Health Core, EtougEbe Baptist Hospital Yaoundé
Coordinator of this site? Confirm its status
YaoundéCameroonRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.