NCT06670651Enrolling by invitation
LinkSymphoKnee (LSK) Total Knee Replacement System Study - Ultra-congruent (UC)
Source: ClinicalTrials.gov · Last updated 3 Sept 2026
Brief summary (registry, in English)
To collect information about implant performance and patient clinical outcomes in patients undergoing primary total knee arthroplasty with the LinkSymphoKnee total knee replacement system with ultra-congruent tibial bearing surface.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 600 (estimated)
- First submitted
- 31 Oct 2024
- Start date
- 21 Mar 2025
- Primary completion date
- Dec 2031
- Lead sponsor
- LinkBio Corp.
- Diseases
- Rheumatoid arthritis
- NCT number
- NCT06670651
What you commit to
- Study type: Observational
- Planned participants: 600
- From 21 Mar 2025 to the primary completion date, Dec 2031
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Women who are pregnant at the time of surgery,
- Previous history of bone disease (e.g., severe osteoporosis or osteomalacia) which in the surgeon's opinion is severe enough to compromise device fixation,
Other illness
- History of joint sepsis,
- Systemic conditions affecting bone density (e.g., inflammatory arthritis or renal disease) which in the surgeon's opinion are severe enough to compromise device fixation,
Age
- 80 years of age or older,
Other
- Bone defect that requires grafting,
- A poorly functioning contralateral total knee replacement or a contralateral revision regardless of function.
Who the study is looking for
- 18 years or older, and skeletally mature; and
- Undergoing a primary TKA for one or both knees using the cemented LinkSymphoKnee knee system as part of the surgeon's standard of care.
- Able to read and understand English (because patient-reported outcome questionnaires are not validated for all potential other languages).
Age in the registry: 18 years to 79 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| OrthoAlabama Spine & Sports Coordinator of this site? Confirm its status | Birmingham | United States | Unknown status |
| Illinois Bone and Joint Institute Coordinator of this site? Confirm its status | Libertyville | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.