NCT06672471Enrolling by invitation
Post-Operative Antibiotic Efficacy in Clean Contaminated Head and Neck Surgery: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 13 Dec 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The "Post-Operative Antibiotic Efficacy in Clean Contaminated Head and Neck Surgery" (PEACH) trial is a study designed to assess the necessity of post-operative antibiotics for preventing surgical site infections (SSIs) in clean-contaminated head and neck surgeries. Recognizing the pivotal role antibiotics have played since their discovery in reducing postoperative infections, this trial aims to determine if a single perioperative antibiotic dose can effectively prevent SSIs, or if additional post-operative antibiotics are required. This study addresses a critical issue in the context of rising antibiotic resistance by potentially limiting unnecessary antibiotic use post-surgery while ensuring patient safety. Results could inform future guidelines, optimizing antibiotic use in surgical prophylaxis and contributing to global efforts against antibiotic resistance.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 170 (estimated)
- First submitted
- 1 Nov 2024
- Start date
- 15 Nov 2024
- Primary completion date
- Aug 2025
- Lead sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
- Diseases
- Head and neck cancer
- NCT number
- NCT06672471
What you commit to
- Study type: Interventional
- Planned participants: 170
- From 15 Nov 2024 to the primary completion date, Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients undergoing emergency surgery.
- Patients undergoing palliative surgery.
- Patients undergoing Clean Head and Neck Surgery.
Other illness
- Patients with a history of antibiotic allergies.
- Patients with ongoing infections or those requiring preoperative antibiotics.
- Patients with immunocompromised conditions (e.g., HIV, on immunosuppressive therapy).
Age
- Patients aged less than 18.
Who the study is looking for
- Patients aged 18 years and older.
- Patients undergoing elective Clean-contaminated head and neck surgery.
- Patients who have provided informed consent.
- Patients with a life expectancy of more than 6 months.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shaukat Khanum Memorial Cancer Hospital and Research Centre Coordinator of this site? Confirm its status | Lahore | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.