An Extension Study to Assess Impact of Multiple Sclerosis (MS) on Physical Function and Provide Continued Ocrelizumab Treatment

Prior treatment

• Concurrent participation in any therapeutic clinical trial (other than the parent study)

Other illness

• Study treatment is commercially marketed in the participant's country for the participant-specific disease and is reasonably accessible to the participant
• Any condition that, in the opinion of the investigator, would interfere with the interpretation of participant safety or place the participant at high risk for treatment-related complications
• Known active malignancy or are being actively monitored for recurrence of malignancy
• Known presence of other neurological disorders

Other

• Study treatment is available via Post Trial Access Program (PTAP) in the participant's country and is accessible to the participant
• Permanent premature discontinuation of study treatment for any reason during the parent study or during the time between last treatment in the parent study and the first dose of study treatment in this extension study (if applicable)
• Immunocompromised state

• Participants who were on ongoing ocrelizumab treatment on one of the following parent-studies \[Studies MN39159/CONSONANCE (NCT03523858), BN42082/MUSETTE (NCT04544436), BN42083/GAVOTTE (NCT04548999), BN44083/GLOBEAM, MN43978/CONSONANCE Ext., WA40404/O'HAND (NCT04035005), MN43964/OLERO (NCT05269004), GN41791/FENTREPID (NCT04544449), BP46016/MINTAKA, CN41144/OCARINA I-SC (NCT03972306), CN42097/OCARINA II-SC (NCT05232825)\] at the time of roll-over and who do not have access to the ocrelizumab treatment locally
• The first dose of study treatment in this extension study will be received no earlier than 5 months after the last treatment in the parent study
• Negative urine pregnancy test within 24 hours to first dose administered on MN45053 study treatment in participants of childbearing potential