NCT06676124Completed
MMP-9/NGAL Modulation by Piper Crocatum in Early Diabetic Nephropathy
Modulation of MMP-9/NGAL Ratio in Diabetic Patients With Early Renal Dysfunction by Piper Crocatum Functional Foods
Source: ClinicalTrials.gov · Last updated 6 Nov 2024
Brief summary (registry, in English)
The goal of this clinical trial is to determine whether functional foods made with Piper crocatum (red betel leaf) can reduce kidney damage markers in people with diabetes who have early kidney dysfunction. Researchers aim to find out if these foods can help decrease inflammation and oxidative stress, which are known to worsen kidney problems in diabetes. Participants are divided into two groups: one group will consume cookies containing Piper crocatum extract, while the other group will consume similar cookies without the extract (placebo). They will eat these cookies twice a day for 12 weeks. This study will measure changes in two main kidney damage markers-MMP-9 and NGAL-before and after the intervention to see if Piper crocatum helps lower these markers and supports kidney health.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 387 (actual)
- First submitted
- 4 Nov 2024
- Start date
- 15 Jun 2024
- Primary completion date
- 5 Sept 2024
- Lead sponsor
- Hasanuddin University
- Diseases
- Chronic kidney disease
- NCT number
- NCT06676124
What you commit to
- Study type: Interventional
- Participants enrolled: 387
- From 15 Jun 2024 to the primary completion date, 5 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients currently undergoing therapy for hypoalbuminemia.
Other illness
- Patients with other medical conditions that require intensive care.
- Known allergies to any ingredients in the study cookies.
- Other chronic conditions that might interfere with the study protocol (e.g., severe cardiovascular disease).
Other
- Pregnant or breastfeeding individuals.
Who the study is looking for
- Adults aged over 20 years.
- Diagnosed with Diabetes Mellitus (DM).
- Serum urea levels above 43 mg/dL or serum creatinine levels above 0.90 mg/dL.
Age in the registry: 21 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Public Health Center in Makassar, Indonesia Coordinator of this site? Confirm its status | Makassar | Indonesia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.