NCT06676397Not yet recruiting
Homeostatic Roles of Eosinophils in Asthma
Characterization of the Homeostatic Functions of Eosinophils in Asthma: An Exploratory Study
Source: ClinicalTrials.gov · Last updated 6 Nov 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The HOMEOS study is an exploratory, observational, and monocentric research. It focuses on characterizing the homeostatic roles of eosinophils in severe asthma. The primary objective is to identify eosinophil subpopulations among different groups of severe asthmatic patients using flow cytometry. The study aims to advance understanding of eosinophil diversity, which could guide new therapeutic approaches .
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 11 Oct 2024
- Start date
- 4 Dec 2024
- Primary completion date
- 4 Dec 2026
- Lead sponsor
- Centre Hospitalier Universitaire de Besancon
- Diseases
- Asthma
- NCT number
- NCT06676397
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 4 Dec 2024 to the primary completion date, 4 Dec 2026
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Treatment with corticosteroids within 10 days prior to inclusion
Other illness
- Coexistence of a chronic eosinophilic inflammatory condition other than asthma
- Other respiratory conditions (cystic fibrosis, COPD, allergic bronchopulmonary aspergillosis, etc.)
- Active smoking or a smoking history of more than 20 pack-years
Other
- Non-eosinophilic asthma
- Pregnant women
- Legal incapacity or limited legal capacity
- Subject unlikely to cooperate with the study and/or with anticipated low cooperation as assessed by the investigator
- Subject without health insurance
- Subject currently in an exclusion period of another study or as indicated by the "national registry of volunteers."
Who the study is looking for
- Patients diagnosed with mild asthma with severe asthma (Biologic-naïve, responders to anti-eosinophil biologic therapies and resistant to anti-eosinophil biologic therapies), control subjects without asthma
- Signature of informed consent
- Affiliation with the French social security system
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.