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NCT06680154Completed

Induction and Stabilization of Gamma Oscillations With 40 Hz External Brain Stimulation

Gamma Oscillations and Working Memory Following Combined 40Hz tACS and iTBS

Source: ClinicalTrials.gov · Last updated 18 Mar 2026

Brief summary (registry, in English)

The goal of the present studies is to develop and validate novel stimulation protocols for the entrainment of gamma oscillations, which are associated with many cognitive functions and critically involved in cognitive impairment such as Alzheimer's disease. In this proposal, combination of repetitive transcranial magnetic stimulation (rTMS) and transcranial alternating current stimulation (tACS), which has been shown effective for the induction, and stabilisation of alpha and theta frequencies in our forgoing studies, will be adopted to the gamma frequency range and applied on prefrontal regions as well as model-based cortical areas to enhance and stabilize gamma oscillations, thereby facilitating cognition

Status (registry)
Completed
Study type
Interventional
Enrollment
30 (actual)
First submitted
5 Nov 2024
Start date
13 Jul 2021
Primary completion date
30 Nov 2023
Lead sponsor
The National Brain Mapping Laboratory (NBML)
NCT number
NCT06680154

What you commit to

  • Study type: Interventional
  • Participants enrolled: 30
  • From 13 Jul 2021 to the primary completion date, 30 Nov 2023
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Taking CNS medication
  • having metal implants

Other illness

  • history of neurological or psychiatric disorders including seizures or epilepsy,

Other

  • current pregnancy

Who the study is looking for

  • normal or corrected to normal eye vision
  • right-handed
  • non-smokers
  • being 18-60 years old
  • providing written informed consent

Age in the registry: 18 years to 60 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Leibniz-Institut für Arbeitsforschung
Coordinator of this site? Confirm its status
DortmundGermanyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.