NCT06682078Completed
Disorders of Sexual Development and Gonadal Tumor Risk
DEV-GEN-RiTuGo - Assessment of Individual Gonadal Tumor Risk in Patients With Disorders of Sexual Developpment According to the Etiology.
Source: ClinicalTrials.gov · Last updated 13 Apr 2025
Brief summary (registry, in English)
Disorders of Sexual Development are rare and represent a spectrum of heterogeneous pathologies. The risk of developing a malignant gonadal germ cell tumor (MGCT) exists and varies according to the etiology. The indication for prophylactic gonadectomy must be modulated and discussed for all patients. It is essential to assess each patient's individual risk. The aim of our study is to assess gonadal tumor risk in patients with Disorders of Sexual Development according to etiology The primary objective is to evaluate tumor risk and the indication for gonadectomy in cases of Disorders of Sexual Development according to etiology. The secondary objectives are to evaluate the timing of gonadectomy, to monitor changes in practice over time, and to assess the contribution of imaging and/or biological tests to tumor detection.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 80 (actual)
- First submitted
- 22 Aug 2023
- Start date
- 1 Sept 2023
- Primary completion date
- 1 Dec 2023
- Lead sponsor
- Hospices Civils de Lyon
- Diseases
- Childhood cancers
- NCT number
- NCT06682078
What you commit to
- Study type: Observational
- Participants enrolled: 80
- From 1 Sept 2023 to the primary completion date, 1 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Biopsies without gonadectomy
- Fetus
- Operated outside the period 1990-2022
- Lack of clinical data
- No karyotype
Who the study is looking for
- Patients who underwent gonadectomy for variation in genital development between 1990 and 2022.
- Pathological anatomy examination in Lyon
- With clinical data
- With karyotype
- 3 categories:
- with genetic diagnosis
- without genetic diagnosis because searched but not found
- without genetic diagnosis because not searched
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Service de Chirurgie uro-viscérale pédiatrique Coordinator of this site? Confirm its status | Bron | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.