NCT06682481Recruiting
Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function
Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function: From Mice to Children
Source: ClinicalTrials.gov · Last updated 18 May 2026
Brief summary (registry, in English)
The investigators will measure blood levels of 1,5-anhydroglucitol in obese children with or without type 2 diabetes and correlate them with parameters related to functional beta-cell mass and glucose metabolism. The values will be compared to those obtained in healthy volunteers. The aim of the study is to test the validity of 1,5-anhydroglucitol as a novel biomarker of beta-cell mass and function in children with obesity with or without type 2 diabetes.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 7 Nov 2024
- Start date
- 22 Nov 2024
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Philippe Klee, MD-PhD
- Diseases
- Obesity, Type 2 diabetes
- NCT number
- NCT06682481
What you commit to
- Study type: Observational
- Planned participants: 50
- From 22 Nov 2024 to the primary completion date, 31 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients treated with an oral antidiabetic drug, glucagon-like peptide-1 analogues or insulin at the time of or less than 2 weeks prior to inclusion.
- Patients treated with a drug known to affect liver function
Other illness
- Patients with diabetes mellitus and positive autoantibodies against islets, insulin, islet antigen 2, glutamic acid decarboxylase or Zinc transporter 8.
- Patients with known liver disease (other than NAFLD)
Who the study is looking for
- Children aged 12 to 16 years
- Obesity. Defined as a body-mass index above the 97th percentile.
- Ability to give informed consent as documented by signature
Age in the registry: 12 years to 16 years · Sex: All
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital of Geneva Coordinator of this site? Confirm its status | Geneva | Switzerland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.