NCT06682832Recruiting
Comparison of Clinical Status of Individuals With COPD and Preserved Ratio Impaired Spirometry
Comparison of Exercise Capacity, Muscle Strength and Oxygenation, Arterial Stiffness, Physical Activity and Quality of Life in Individuals With Chronic Obstructive Pulmonary Disease and Impaired Spirometry With Preserved Ratio
Source: ClinicalTrials.gov · Last updated 31 Mar 2026
Brief summary (registry, in English)
Despite the globally varying high prevalence rate of the PRISm phenotype, there are no guidelines for its diagnostic evaluation and management. Further studies are needed on appropriate approaches for individuals with PRISm to improve respiratory symptoms and prognosis. As research continues to evolve, PRISm needs to be recognized as a critical component of pulmonary assessments and at-risk individuals need to be provided with appropriate treatment and follow-up to prevent progression to COPD. There are no studies in the literature comparing PRISm, respiratory muscle strength, peripheral muscle strength and oxygenation, arterial stiffness, physical activity level and sleep level in COPD and healthy individuals. The aim of this study was to compare respiratory muscle strength, peripheral muscle strength and oxygenation, arterial stiffness, physical activity level and sleep level in PRISm, COPD and healthy subjects.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 54 (estimated)
- First submitted
- 6 Nov 2024
- Start date
- 18 Sept 2025
- Primary completion date
- Sept 2026
- Lead sponsor
- Hacettepe University
- Diseases
- COPD
- NCT number
- NCT06682832
What you commit to
- Study type: Observational
- Planned participants: 54
- From 18 Sept 2025 to the primary completion date, Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe orthopaedic, neurological and cardiac diseases
- Severe orthopaedic, neurological and cardiac diseases,
- Having a known chronic disease,
Other
- PRISm group exclusion criteria;
- Being diagnosed with COPD,
- Not volunteering to participate in the study
- Being in COPD exacerbation period,
- Not volunteering to participate in the study.
- Healthy individuals exclusion criteria;
- Not volunteering to participate in the study
Who the study is looking for
- PRISm group inclusion criteria;
- Being \>40 years old,
- Being diagnosed with PRISm,
- Volunteering to participate in the study,
- Not having any orthopaedic or neurological problems that may prevent participation in the measurements,
- Co-operation with measurements
- Being \>40 years old,
- Being diagnosed with COPD,
- To be clinically stable,
- Volunteering to participate in the study.
- Being \>40 years old,
- Volunteering to participate in the study,
- No known chronic health problems,
- To be able to co-operate with the measurements.
Age in the registry: 40 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hacettepe University Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.