NCT06684249Recruiting
Efficacy of Nerve Block Versus Botox in Chronic Migraine Management
A Randomized Controlled Trial Comparing the Efficacy of Supratrochlear and Greater Occipital Nerve Blocks to Botulinum Toxin A in the Management of Chronic Migraine
Source: ClinicalTrials.gov · Last updated 12 Nov 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this clinical trial is to determine whether nerve block injections (specifically, supratrochlear and greater occipital nerve injections) are as effective as Botulinum toxin A (Botox) injections in treating chronic migraine in adults. The main questions it aims to answer are: * Do nerve block injections reduce the number of monthly migraine days compared to baseline? * Are there any differences in the frequency of migraine-related symptoms between the nerve block and Botox treatment groups? * Which treatment leads to higher patient satisfaction and improved quality of life? Participants in this study will: * Receive either nerve block injections or Botox injections every 12 weeks. * Visit the clinic once every month for follow-ups and assessments. * Maintain a headache diary to record the frequency and severity of their migraines and any adverse effects experienced. * Researchers will compare the outcomes of the two groups to determine if one treatment is superior in terms of efficacy and patient satisfaction.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 64 (estimated)
- First submitted
- 10 Nov 2024
- Start date
- 10 Nov 2024
- Primary completion date
- 10 May 2025
- Lead sponsor
- Zagazig University
- Diseases
- Migraine
- NCT number
- NCT06684249
What you commit to
- Study type: Interventional
- Planned participants: 64
- From 10 Nov 2024 to the primary completion date, 10 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous nerve block or Botox treatment within the last 6 months.
Other illness
- History of allergy or hypersensitivity to local anesthetics or Botulinum toxin.
- Significant comorbid psychiatric or neurological disorders that could interfere with study participation or evaluation.
Other
- Pregnancy or breastfeeding.
- Contraindications to either treatment as per product labels.
Who the study is looking for
- Adults aged 18 to 65 years.
- Diagnosis of chronic migraine, defined as having headaches on 15 or more days per month for more than three months, with at least 8 of those days meeting criteria for migraine.
- Ability to provide informed consent and comply with study requirements.
- No changes in prophylactic migraine medications in the last 3 months.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Zagazig University, Faculty of Medicine Coordinator of this site? Confirm its status | Zagazig | Egypt | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.