NCT06688396Recruiting
Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)
Dilated Cardiomyopathy Detection Using Artificial Intelligence and Screening With Mobile Technology
Source: ClinicalTrials.gov · Last updated 30 Jan 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This is a prospective, single-arm clinical trial in which participants with dilated cardiomyopathy will invite their first degree relatives to undergo mobile cardiac, electrocardiogram screening.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 12 Nov 2024
- Start date
- 4 Dec 2024
- Primary completion date
- Dec 2026
- Lead sponsor
- Lancaster General Hospital
- Diseases
- Heart failure
- NCT number
- NCT06688396
What you commit to
- Study type: Interventional
- Planned participants: 150
- From 4 Dec 2024 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Proband has previously informed FDR to undergo cardiac screening
- Previously informed about cardiac screening or has completed cardiac screening by transthoracic echocardiogram (TTE)
Other illness
- Congenital structural heart disease
- Severe and untreated or untreatable hypertension
- Cardiomyopathy due to acute or reversible conditions; examples include tachyarrhythmias, thyroid disorders, iron overload
Lab values
- Ischemic cause of reduced LVEF
- evidence of myocardial infarction, inducible ischemia or chest pain on stress testing in absence of coronary angiogram to rule out ischemic disease
- history of acute coronary syndromes (STEMI (ST-Elevation Myocardial Infarction), NSTEMI (Non-ST-Elevation Myocardial Infarction) or unstable angina) revascularization or ≥75% stenosis of either left main or Left Anterior Descending (LAD) or ≥75% stenosis of 2 major epicardial vessels on angiogram
- Any secondary cause of reduced LVEF such as pregnancy, myocarditis, amyloidosis, sarcoidosis, exposure to toxins including alcohol, substance abuse or chemotherapeutic drug
- Previously diagnosed with reduced LVEF
Other
- DCM attributed to any other secondary form of cardiomyopathy per the investigator's determination
- Moderate or greater primary valvular abnormality not due to underlying cardiomyopathy
- (CPC Participants only) Home address outside of traveling range
- (CPC Participants only) Home address outside of traveling range
Who the study is looking for
- Male or female age ≥ 18 years
- Confirmed diagnosis of non-ischemic DCM determined at the discretion of the treating physician and defined as LVEF ≤ 45% at any time during the clinical course of the patient
- Must have at least one living adult FDR
- Able to provide informed consent
- Male or female age ≥ 18 years who are first-degree relatives of patients with DCM
- Proband has provided informed consent
- FDR able to provide informed verbal consent
- Access to a smartphone or digital tablet with cellular data or Wi-Fi access
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lancaster General Hospital Coordinator of this site? Confirm its status | Lancaster | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.