NCT06689267Completed
Initial CT Perfusion-Guided Strategy for Suspected NSTEMI
Initial CT Perfusion-Guided Strategy Versus Invasive Coronary Angiography in Patients With Suspected Non-ST-Segment Elevation Myocardial Infarction
Source: ClinicalTrials.gov · Last updated 3 Mar 2026
Brief summary (registry, in English)
Non-ST elevation myocardial infarction (NSTEMI) is a relatively complex type of myocardial infarction, characterized by chest pain symptoms and elevated troponin levels. However, some patients initially diagnosed with suspected NSTEMI are found not to have severe stenosis upon coronary angiography. Recent studies have shown that initial imaging examinations (including CTA and CMR) in suspected NSTEMI patients can help reduce the need for coronary angiography. The diagnostic value of CT perfusion (CTP) has been established in patients with stable coronary artery disease, but relevant studies have not yet been conducted in suspected NSTEMI patients. This study aims to explore the diagnostic and therapeutic value of an initial CTP strategy for suspected NSTEMI patients. Additionally, we will conduct a cardiovascular health questionnaire to investigate the impact and prognostic value of factors such as adverse lifestyle and inflammation levels in these patients.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 180 (actual)
- First submitted
- 12 Nov 2024
- Start date
- 1 Dec 2024
- Primary completion date
- 28 Feb 2026
- Lead sponsor
- Shanghai Zhongshan Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT06689267
What you commit to
- Study type: Interventional
- Participants enrolled: 180
- From 1 Dec 2024 to the primary completion date, 28 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known history of coronary artery disease
- Coexisting conditions such as pregnancy, cancer, severe valvular heart disease, or liver/kidney dysfunction
- Other diseases with a life expectancy of less than one year
Other
- Persistent chest pain or ECG indicating dynamic ST-T changes,
- Hemodynamic instability
- Contraindications for CT perfusion or coronary angiography
- Inability to sign informed consent or, in the researcher's judgment, poor compliance, making it unlikely the patient can complete the study as required.
Who the study is looking for
- Patients with stable chest tightness or chest pain, aged ≥18 years
- No ST elevation or dynamic ST-T changes on the ECG
- Elevated TNT (greater than 14 ng/L three hours after symptom onset)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Zhongshan Hospital,Fudan University Coordinator of this site? Confirm its status | Shanghai | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.