NCT06691100Recruiting
How a Single Workout Affects Gut Bugs in Women With Different Fitness Levels and Body Types
The Acute Effects of an Endurance Exercise Bout the Gut Microbiome and Gut-derived Metabolome in Women's Distinct Fitness and Body Mass Indexes
Source: ClinicalTrials.gov · Last updated 9 Sept 2026
Brief summary (registry, in English)
This study aims to elucidate the differences in the gut microbiome functional activity and metabolome in adult premenopausal women with distinctive fitness levels and BMIs (with obesity, w/o obesity). The specific aims are as follows: * Aim 1: To examine the effects of acute aerobic exercise at 60-70% heart rate reserve (HRRmax) for 30 minutes bout on changes in the abundance of SCFA-producing bacteria and their functional downstream metabolic activity. * Aim 2: To examine the effects of acute aerobic exercise at 60-70% HRRmax 30-minute bout on changes in GM-released SCFA concentrations in stool and plasmatic metabolome.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 12 Nov 2024
- Start date
- 16 Oct 2024
- Primary completion date
- 1 Jun 2027
- Lead sponsor
- George Washington University
- Diseases
- Obesity
- NCT number
- NCT06691100
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 16 Oct 2024 to the primary completion date, 1 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently taking any herbal, fiber, or prebiotic supplement
- Current or 1-month before the study, taking oral or vaginal antibiotics
Other illness
- Diagnosed with any gastrointestinal, endocrine, digestive, cancer, or cardiovascular disease.
Age
- Currently pregnant, \< 2 years postpartum, lactating
Other
- Biological sex: male
- BMI \< 19 kg/m2 or \> 40 kg/m2
Who the study is looking for
- Biological sex: female
- BMI 19 to 24.99 kg/m2 or BMI 30-40 kg/m2
- Exercisers: Exercise at least 4 times per week for 60 minutes (a total of 240 minutes per week) on a programmed exercise training either on endurance sports (e.g., running, cycling, triathlon), strength (e.g., powerlifting), or team sports (e.g., rugby, football, soccer)
- Non-Exercisers: Sedentary individuals who have not reached the PA guidelines (150 minutes of moderate-intensity physical activity a week, 75 minutes of vigorous-intensity physical activity, or an equivalent combination of moderate and vigorous-intensity physical activity).
Age in the registry: 21 years to 40 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Milken Institute School of Public Health, The George Washington University Coordinator of this site? Confirm its status | Washington D.C. | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.